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Vitamin B12 deficiency and metformin

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The applicant also asserted that beneficiary access is at risk if CMS payment policies do not reflect the actual cost of providing custom-made, anatomically-designed interbody fusion device technology, like the aprevo Cervical ACDF System, to more Medicare beneficiaries

However, neurological symptoms related to low vitamin B12 may still continue if the underlying deficiency is not addressed

In a 56-day phase-2 trial, 9 participants with severe dry eye syndrome were treated with synthetic TB4 eye drops or placebo for 28 days, followed by a 28-day observational period